[horde] Problem in using horde 2.2.5

[Sandeep Yadav]

I am a hosting member with account name:
 sandeep.xoopiter.com
I uploaded horde 2.2.5 in "sandeep.xoopiter.com/email"
When I request this site following error occurs:
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Warning: main(): SAFE MODE Restriction in effect. The script whose uid is 3493 is not allowed to access /usr/lib/php/PEAR.php owned by uid 0 in /home/vhosts/sandeep.xoopiter.com/email/lib/Registry.php on line 13
Warning: main(PEAR.php): failed to open stream: Permission denied in /home/vhosts/sandeep.xoopiter.com/email/lib/Registry.php on line 13
Fatal error: main(): Failed opening required 'PEAR.php' (include_path='.:/usr/lib/php:/usr/local/lib/php') in /home/vhosts/sandeep.xoopiter.com/email/lib/Registry.php on line 13
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line 13 of /home/vhosts/sandeep.xoopiter.com/email/lib/Registry.php
is:
require_once 'PEAR.php';
Please tell me if u know where the problem is?
sincerely,
sandeep.xoopiter.com